传染性皮下及造血组织坏死病毒致病性研究进展

摘要

传染性皮下及造血组织坏死病毒(IHHNV)是一种分布较广、危害较大的对虾病毒,已被世界动物卫生组织(OIE)列为须向其申报的甲壳类重要疫病病原.IHHNV在我国已形成了一定的流行趋势,目前仍是严重危害我国养殖虾类的重要病毒.本文从IHHNV的流行地区及危害、宿主、致病类型、对宿主不同年龄阶段的致病性差异、与白斑综合征病毒(WSSV)的干扰作用、感染机制和致病机理方面,综述了与IHHNV致病性相关的研究进展,以期为进一步深入研究IHHNV防控提供参考资料.%Globally, infectious hypodermal and haematopoietic necrosis virus (IHHNV) is one of the major viral pathogens of penaeid shrimp, causing huge economic loss to the shrimp farming industry. Further, IHHNV has been listed as a reportable crustacean disease pathogen by the World Organization for Animal Health (OIE). It is widely distributed in China and has become an important virus affecting shrimp culture. In the present paper, IHHNV pathogenicity-related progress geographically, host range, pathogenicity type, pathogenicity in host at different growth stages, interference with white spot syndrome virus (WSSV), and pathogensis mechanism of IHHNV were reviewed. The paper aimed to provide systematic references for the studies on control of IHHNV.