Objective To investigate the impact of homolateral transient ischemic attack on prognosis in patients with secondary cerebral infarction.Methods A total of 270 patients with secondary cerebral infarction were selected in the People′s Hospital of Shen County of Liaocheng from December 2013 to December 2015,and they were divided into A group(less than 50 years old,n=80),B group(equal or over 55 years old but equal or less than 70 years old,n=130)and C group(over 70 years old,n=60)according to age;according to the incidence of homolateral transient ischemic attack,patients of A group were divided into A1 group(with homolateral transient ischemic attack,n=22)and A2 group(without homolateral transient ischemic attack,n=58),patients of B group were divided into B1 group(with homolateral transient ischemic attack,n=34)and B2 group(without homolateral transient ischemic attack,n=96),patients of C group were divided into C1 group(with homolateral transient ischemic attack,n=19)and C2 group(without homolateral transient ischemic attack,n=41).Difference of NIHSS score at admission and after 1 month of treatment,Barthel index after 1 month of treatment and collateral circulation establishment after admission were compared among A group,B group and C group,between A1 group and A2 group,between B1 and B2 group,between C1 group and C2 group.Results There were statistically significant differences of difference of NIHSS score at admission and after 1 month of treatment and Barthel index after 1 month of treatment among A group,B group and C group(P<0.05),while no statistically significant differences of collateral circulation establishment after admission was found among A group,B group and C group(P>0.05).No statistically significant differences of difference of NIHSS score at admission and after 1 month of treatment was found between A1 group and A2 group(P>0.05);Barthel index after 1 month of treatment of A1 group and proporation of patients with good collateral circulation establishment after admission of A1 group were statistically significantly higher than those of A2 group(P<0.05).No statistically significant differences of difference of NIHSS score at admission and after 1 month of treatment was found between B1 group and B2 group(P>0.05);Barthel index after 1 month of treatment of B1 group and proporation of patients with good collateral circulation establishment after admission of B1 group were statistically significantly higher than those of B2 group(P<0.05).No statistically significant differences of difference of NIHSS score at admission and after 1 month,Barthel index after 1 month of treatment or collateral circulation establishment after admission was found between C1 group and C2 group(P>0.05).Conclusion Homolateral transient ischemic attack can effectively improve the prognosis and promote the collateral circulation establishment in patients with secondary cerebral infarction,but there is no obvious impact on patients over 70 years old.%目的 探讨同侧短暂性脑缺血发作(TIA)对继发脑梗死患者预后的影响.方法 选取聊城市莘县人民医院2013年12月-2015年12月收治的继发脑梗死患者270例,根据年龄分为<55岁者80例(A组)、55~70岁者130例(B组)、>70岁者60例(C组);根据同侧TIA发生情况将A组患者分为A1组(发生同侧TIA,n=22)和A2组(未发生同侧TIA,n=58),将B组患者分为B1组(发生同侧TIA,n=34)和B2组(未发生同侧TIA,n=96),将C组患者分为C1组(发生同侧TIA,n=19)和C2组(未发生同侧TIA,n=41).比较不同年龄段及相同年龄段不同TIA发生情况患者入院时与治疗1个月后美国国立研究院卒中量表(NIHSS)评分差值、治疗1个月后Barthel指数(BI)评分及入院后侧支循环建立情况.结果 3组患者入院时与治疗1个月后NIHSS评分差值和治疗1个月后BI评分比较,差异有统计学意义(P<0.05);3组患者入院后侧支循环建立情况比较,差异无统计学意义(P>0.05).A1组和A2组患者入院时与治疗1个月后NIHSS评分差值比较,差异无统计学意义(P>0.05);A1组患者治疗1个月后BI评分及入院后侧支循环建立良好率高于A2组(P<0.05).B1组和B2组患者入院时与治疗1个月后NIHSS评分差值比较,差异无统计学意义(P>0.05);B1组患者治疗1个月后BI评分及入院后侧支循环建立良好率高于B2组(P<0.05).C1组和C2组患者入院时与治疗1个月后NIHSS评分差值、治疗1个月后BI评分及入院后侧支循环建立情况比较,差异均无统计学意义(P>0.05).结论 同侧TIA可有效改善继发脑梗死患者预后并促进侧支循环建立,但对>70岁的继发脑梗死患者则无明显影响.
展开▼
