西门子1．5T磁共振对乳腺肿瘤的诊断及鉴别诊断价值

摘要

Objective To investigate the diagnosis and differential diagnosis of Siemens 1.5T MRI for breast cancer. Methods 60 female breast cancer patients,including 34 patients of benign lesions and 26 patients of malignant lesions,received Siemens 1.5T MRI for enhance MRI and conventional MRI detecting.Results MRI image quality were satisfactory in all pa-tients that can meet the diagnostic needs;before and after contrast injection in DWI lesion can be observed the dynamic enhance-ment.SNR of benign lesions of DWI were (52.6 ±4.75),after enhanced were (53.74 ±5.72) (b=0);SNR of breast cancer of DWI were (34.75 ±4.12) (b=0),after enhanced were (35.51 ±3.87) (b=0),there had were statistically significant differ-ences (P<0.05).ADC values of breast cancer before and after enhancement were (1.09 ±0.26) ×10 -3 mm2/s and (0.97 ± 0.27) ×10 -3 mm2/s,ADC values of benign lesions before and after enhancement were (1.49 ±0.26) ×10 -3 mm2/s and (1.46 ±0.22) ×10 -3 mm2/s,there had were statistically significant differences (P<0.05).ADC values under the ROC curve were 0.94,95 after enhancement MRI,and the 95%confidence interval were 0.86~1.00,diagnostic threshold was 1.20 ×10 -3 mm2/s,the sensitivity and specificity were 87.5%and 90.9%.Conclusion Siemens 1.5T MRI for breast cancer has good im-age diagnostic value,and it is of great value in the differential diagnosis of benign and malignant lesions.%目的：探讨西门子1．5T磁共振对乳腺肿瘤的诊断及鉴别诊断价值。方法对60例女性乳腺肿瘤患者选择西门子1．5T磁共振进行常规MRI与增强MRI检查。结果所有患者的MRI图像质量满意，均能满足诊断需要；注射对比剂前后在DWI中可观察到病灶在动态增强。增强前良性病灶DWI图像的SNR为（52．6±4．75），增强后为（53．74±5．72）（b＝0）；增强前乳腺癌DWI图像SNR为（34．75±4．12）（b＝0），增强后为（35．51±3．87）（b＝0），组间对比差异都有统计学意义（P＜0．05）。乳腺癌增强前后的ADC值分别为（1．09±0．26）×10－3 mm2／s和（0．97±0．27）×10－3 mm2／s，良性病灶增强前后的ADC值分别为（1．49±0．26）×10－3 mm2／s和（1．46±0．22）×10－3 mm2／s，组间对比差异也有统计学意义（P＜0．05）。增强后MRI的ADC值ROC曲线下面积为0．94，95％可信区间为0．86～1．00，诊断阈值1．20×10－3 mm2／s，敏感度及特异度分别为87．5％和90．9％。结论西门子1．5T磁共振对乳腺肿瘤有很好的图像显示诊断效果，对良恶性病变的鉴别诊断具有重要价值。