Objective To investigate the clinical features of hepatitis E (HE) in the elderly. Methods The clinical data of 59 elderly patients with HE {the elderly group) and 46 non-elderly patients with HE (the non-elderly group) were analyzed retrospectively. Comparisons were performed to investigate the differences between the two groups. Results The incidence of severe hepatitis in the elderly group was significantly higher than that in the non-elderly group (P < 0.05). The level of serum albumin (ALB) in the elderly group was significantly lower than that in the non-elderly group (P <0.01), whereas the levels of serum total bilirubin (TBIL) and prothrombin time (PT) in the elderly group were significantly higher than those in the non-elderly group (P < 0. 05). The incidence of combined diseases in the elderly group was significantly higher than that in the non-elderly group (P <0. 01 ), The length of hospitalization in the elderly group was significantly longer than that in the non-elderly group (P<0.01). Conclusions With a high incidence, HE in the elderly has more severe liver dysfunction, longer course of disease and higher mortality rate.%目的 探讨老年人戊型肝炎(HE)的临床特征. 方法 回顾性分析59例老年HE患者(老年组)和46例非老年HE患者(非老年组)的临床资料,比较老年组与非老年组之间的差异. 结果 老年组重型肝炎的发生率明显高于非老年组(P＜0.05).老年组白蛋白( ALB)水平明显低于非老年组(P＜0.01),总胆红素(TBIL)水平、凝血酶原时间(PT)明显高于非老年组(P＜0.05).老年组合并症的发生率明显高于非老年组(P＜0.01).老年组住院时间较非老年组明显延长(P＜0.01). 结论 老年人HE多见,肝功能损害重,病程长,病死率高.
展开▼
