Guillain-Barré syndrome (GBS) is an uncommon disease involving widespread peripheral nerve inflammatory demyelination which results in ascending symmetrical limb paralysis and areflexia. Approximately 2/3 of cases occurred following a simple, trivial antecedent infection. In northern China, diarrhea caused by Campylobacter jejuni is the most common etiology of GBS. This article presents 2 cases - post cerebral hemorrhage and post head traumatic GBS. Both patients suffered from acute motor axonal neuropathy, a main subtype of GBS, 14 days after cerebral hemorrhage or head trauma without any antecedent infection. The possible pathophysiological mechanisms are discussed in the article, and the importance of increasing the awareness of early diagnosis, as well as early treatment with intravenous immunoglobulin and supportive care, in this special pathogenic GBS is emphasized.
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