Transplanting neural progenitors to build a neuronal relay across the injured spinal cord

摘要

Cellular transplantation for repair of spinal cord injury is a promising therapeutic strategy that includes the use of a variety of neural and non-neural cells isolated or derived from embryonic and adult tissue as well as embryonic stem cells and induced pluripotent stem cells.In particular,transplants of neural progenitor cells(NPCs)have been shown to limit secondary injury and scar formation and create a permissive environment in the