Lysophospholipids in retinal axon guidance: roles and cell signaling

摘要

Nerve regeneration in the central nervous system(CNS)has become a holy grail of biomedical research.To understand nerve growth that would be required for efficient regeneration,many scientists have turned to developing systems where nerve growth is abundant and normal neural connections are established.One aspect of this neural development,which would also be important in nerve regeneration,is axon guidance–the process by which a growing axon,through its growth cone,is guided to the correct target for synaptic connections.There has been considerable work done on axon guidance in a variety of systems,but one system that has presented many opportunities is the visual system.In the visual system,there is one cell type that provides the output nerve from the eye。