左西孟坦治疗老年重度心力衰竭的临床价值分析

摘要

Objective To analysis efficacy and clinical application value of levosimendan in the treatment of elderly patients with severe heart failure .Methods A total of 80 elderly patients with severe heart fail-ure,randomly divided into observation group and control group .The two groups are to be the conventional treatment, the control group, to be intravenous maintain infusion 5ug/(kg· min) of dobutamine, continu-ous 24h;observation group was treated with intravenous levosimendan initial load 12ug/kg, 10min after intravenous 0.1ug/(kg· min), then intravenous infusion of 0.25~1.0 ug/(kg· min).Results The total effective rate of the observation group was significantly higher than the control group ( P<0 .05 ) , af-ter two weeks of treatment , the indicators of the observation group than in the control group improved more significantly (P<0.05).Conclusion Levosimendan better clinical efficacy for the treatment of elderly patients with severe heart failure , safe , reliable , and better tolerated by patients , worthy of promotion in clinical application .%目的观察左西孟坦治疗老年重度心力衰竭的疗效及临床应用价值。方法将老年重度心力衰竭患者80例随机均分为观察组与对照组。两组均予以常规治疗，对照组予以静脉维持泵注5ug/（ kg· min）的多巴酚丁胺，持续24h；观察组予以静注左西孟坦，初始负荷量为12ug/kg，10min后静注0．1ug/（ kg· min），然后静脉滴注0．25～1．0 ug/（kg· min）。结果观察组的治疗总有效率明显较对照组更高（P＜0．05），治疗2w以后，观察组各项指标较对照组改善更为明显（ P＜0．05）。结论左西孟坦治疗老年重度心力衰竭具有较好的临床疗效，安全可靠，患者的耐受性较好，值得临床推广应用。