目的 探讨唾液幽门螺杆菌(HpS)测试板检测Hp感染的临床筛查价值.方法 对150例临床有消化系统症状的患儿同时行HpS检测和胃镜下胃黏膜组织活检快速尿素酶试验(RUT)检测,并对两者结果进行对比研究.结果 150例患儿中HPS检出阳性65例(43.33%),胃镜RUT检出阳性41例(27.33%),阳性符合率(敏感性)为85.37%,阴性符合率(特异性)为72.48%;阳性预测值为53.85%,阴性预测值为92.94%.结论 HPS具有操作简便、快速、无创、准确等优点,是临床筛查Hp感染的一种很有价值的方法.%Objective To study on the clinical screening value of the test plate in detection of Helicobacter pylori in saliva ( HPS ). Methods HPS test plate was used to detect urease in saliva of 150 children with gastrointestinal symptoms,while rapid urease test ( RUT ) was also used to detect urease in mucosa of stomach under gastroendoscopy. And the results detected by the two methods above were compared. Results In 150 patients,65 cases ( 43.33％ ) were detected to be positive by HPS, while 41 cases ( 27.33％ )were detected to be positive by RUT. The positive rate matched of HPS with RUT ( sensitivity ) was 85.37％ ,while the negative rate matched ( specificity ) was 72.48％. The positivepredictiverate was 53.85 ％, while the negative predictive rate was 92.94 ％. Conclusion HPS is featured with non-invasive, easily operating, rapid, and accurate, etc. , which is a valuable screening method in detection of Hp infection.
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