肝豆状核变性的CT诊断与临床分析

摘要

Objective To improve the computed tomography ( CT ) diagnostic accuracy and the understanding of hepatolenticular degeneration( HLD ) by analyzing CT features in the brain. Methods 10 cases of HLD were collected, which were confirmed by biochemistry and diagnostic therapy. Both the CT features and clinical manifestations were evaluated retrospectively. Results In 10 cases of HLD,9 cases showed the symmetrical hypodense lesions in the both sides of the basal ganglia ( especially lentiform nucleus ) in the brain ,6 cases in the bilateral thalamus ,2 cases in the brainstem ,2 cases in the cerebellar,9 cases showed various degrees of brain atrophy. Conclusion CT appearance of HLD have characteristic features in the brain .So CT has important value to guide the diagnosis and treatment.%目的 分析肝豆状核变性(HLD)的颅脑CT表现特征,提高对该病的认识及诊断准确率.方法 收集经生化检测及诊断性用药确诊的10例HLD患者的检查资料,回顾性分析CT征象及临床表现.结果 10例HLD患者中,脑基底节(尤其是豆状核)区对称性低密度病灶9 例,丘脑对称性低密度病灶6例,脑干低密度病灶2例,小脑低密度病灶2例,有不同程度的脑沟增宽等脑萎缩表现9例.结论 HLD的颅脑CT表现具有特征性,对临床诊断及治疗具有重要意义.