乌司他丁对多器官的保护作用

摘要

急危重疾病、重大手术、器官移植及其引发的病理过程可以对机体器官产生不同程度的损害,而有效的药物应用可能会降低各主要器官的损害程度.乌司他丁是从健康成年男性尿液中分离纯化出来的一种胰蛋白酶抑制剂,无免疫原性,可抑制胰酶、溶酶体、炎性介质的过度释放,抑制心肌抑制因子的产生,清除氧自由基,稳定溶酶体膜,改善微循环,对全身各主要脏器产生重要的器官保护作用.%Anita and critical illness,major surgery, organ transplantation,and the resulted pathological process can produce different degrees ol damage to body organs,the effective application ol medicationrnline of healthy adult males,which is non - immnnogenic,and can inhibit the excessive release of trypsin, lysosomes,and inflammatory mediators, inhibit the generation of myocardial inhibitory 1 act or, remove oxygen fraa radicals,stablize lysosome membrane,and improve miciociinilation,playing an important role in the protection of multiple major organs.