Hilar cholangio carcinoma is a common malignant tumor. The early diagnosis is difficult be-rause the clinical symptoms usually appear late. The specific anatomir structure of bile duct and its close relation with blood vessel, peripheral nerves and various neuropeptides, peri neural invasiveness and metastasis oi hilar cholangiocarcinoma induce the low radical resection rate and poor prognosis. Radical resection oi cholangiocarcinoma,including extended resection oi invasive blood vessel and metastasis lymph nodes and appliance oi liver transplant can promote the survival rate oi patients. Therefore, finding new surgery treatments for cholangio carcinoma is oi great significance for improving the clinical therapy.%肝门部胆管癌是一种胆道常见恶性肿瘤,临床上出现症状较晚,早期诊断困难,而且肝门部胆管癌所处的解剖位置特殊及其向周围组织、血管、神经浸润的特点,外科根治性切除率低,因而预后较差.实施肝门部胆管癌的根治性切除能够有效地提高患者生存率,包括对于侵犯的血管或转移的淋巴结的扩大切除以及肝移植术的应用均能提高患者的生存率.因此,寻求胆管癌外科手术有效的新的治疗方法,对于提高胆管癌的临床治疗具有十分重要的意义.
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