缺血修饰性白蛋白与2型糖尿病血管并发症

摘要

Ischemia modified albumin( IMA )is an indicator oi widespread endothelial damage and tissue ischemia in type 2 diabetes meliitiis( T2DM ). IMA was firstly iound and majorly studied in patients with my-ocardial ischemia. Current clinical application is mainly ionised on heart diseases such as the diagnosis oi a-cute coronaiy syndrome,risk stratification and myocaidial ischemia. In recent years,the study found that IMA is not only the indicator oi acute myocaidial ischemia, but also important in the early detection and prevention oi vascular complications oi T2DM.%缺血修饰性白蛋白(IMA)是2型糖尿病(T2DM)患者广泛内皮损伤及组织缺血的标志物.IMA首先在心肌缺血的患者中被发现并进行了较多研究.目前临床应用主要是集中于急性冠状动脉综合征的诊断、危险分级和心肌缺血等心脏疾病方面.近年来研究发现IMA不仅是评价急性心肌缺血的指标,对T2DM血管并发症的早期监测和预防也具有重要意义.