急性高原病的病理生理表现及机制研究进展

摘要

Acute mountain sickness( AMS ) is characterized by a series of pathophysiological changes, functional disorders and other related symptoms experienced by people who quickly enter high altitude of over 2500m and low oxygen pressure environment. With the economic development of high altitude regions, a growing number of people work or travel at high altitudes, causing a rise in the morbidity of AMS, which seriously limits recreation and people's health at high altitude. In conclusion,a deeper understanding on mechanisms of AMS has great significance for the active and effective prevention and treatment.%急性高原病(AMS)是人快速进入2500 m以上高原、暴露于低氧环境后产生的具有一系列病理生理学变化、功能紊乱及相应的各种临床症状的疾病.随着高原地区经济建设的迅速发展,进入高原的人逐年增多,高原病的发病率也逐渐增高,已成为制约高原经济发展和影响驻地军民身体健康的主要因素.研究AMS病理生理表现及其发病机制,对积极有效地预防和治疗AMS有重要意义.