目的：探讨银杏达莫注射液治疗冠状动脉粥样硬化性心脏病(冠心病)不稳定型心绞痛的临床治疗效果及应用价值。方法选择2012年3月至2013年3月巨野县人民医院治疗的冠心病不稳定型心绞痛患者144例，按照随机数字表法分为观察组和对照组，各72例。对照组采取西医常规治疗方案，观察组在对照组治疗的基础上联合使用银杏达莫注射液治疗，银杏达莫20 mL+生理盐水250 mL静脉滴注，每日1次，连续治疗21 d。观察两组患者的临床疗效。结果观察组总有效率高于对照组(91．7%比76．4%)，差异有统计学意义(P<0．05)。治疗后，观察组三酰甘油、总胆固醇、低密度脂蛋白胆固醇改善情况优于对照组，差异有统计学意义( P<0．05)。两组不良反应发生率比较差异无统计学意义(P>0．05)。结论在西医常规治疗的基础上联合使用银杏达莫注射液治疗冠心病不稳定型心绞痛临床疗效显著，优于单纯西医常规治疗，可以明显改善患者血脂水平，不良反应轻微。%Objective To investigate the clinical therapeutic effect and application value of ginkgo bilo-bate injection in treatment of unstable angina pectoris of coronary heart disease. Methods A total of 144 patients with unstable angina admitted to Juye County People′s Hospital from Mar. 2012 to Mar. 2013 were randomly divided into the observation group and the control group according to random number table method, 72 cases in eacch group. The control group was treated with conventional western treatment;the observation group was treated with ginkgo bilobate injection based on the control group′s regimen,ginkgo bilobate injection administration:20 mL+ physiological saline 250 mL intravenous drip,once per day,for 21 d continuously. The clinical effect of the two groups were observed. Results Total effective rate of the observation group was higher than that of the control group(91. 7% vs 76. 4%),the difference was statistically significant(P <0. 05). After treatment,three triacylglycerol,total cholesterol,low density lipoprotein cholesterol improvement of the observation group was better than the control group, the difference was statistically significant ( P <0. 05). Adverse reaction rate of the two group had no significant difference(P>0. 05). Conclusion On the basis of conventional western medicine therapy,the combination of ginkgo bilobate injection of unstable angi-na pectoris of coronary heart disease has significant clinical curative effect,which is superior to the pure west-ern medicine routine treatment,and can significantly improve the blood lipid situation of the patients,with only slight adverse reactions.
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