网织红细胞参数在白血病化疗前后中的变化及临床意义

摘要

Objective:To study the change and clinical significance of reticulocyte parameter before and after leukemia chemotherapy.Method:40 patients who were confirmed acute leukemia were chosen,the patients’s blood plateletses,white cell number and net during the chemotherapy knits the red cell number dynamic state variety were observed.Result:The white cell,net of the leukemia sufferer of chemotherapy empress knits red cell and blood platelets to all and sharply lower,ANC and RET#the meeting declined to 0.2×109 and 10×109,HFR’s adding MFR declined to lowest or 0,carry on marrow cytology to the sufferer examination result BE:There was pit cell that will take place to increase to living to lower or extremely lower a phenomenon, LFR builds a blood function creation to repress influence to the sufferer.Conclusion:To RET(the net knits red cell parameter)of leukemia sufferer#carry on a dynamic state monitor observation,in order to judge a building of sufferer’s oneself blood function circumstance to provide a more abundant clinical information,have important reference value and meaning on the clinical treatment.%目的：研究网织红细胞参数在白血病化疗前后的变化及临床意义。方法：选择本院收治的40例确诊为急性白血病的患者，对其在化疗过程中的血小板、白细胞数以及网织红细胞数动态变化进行观察。结果：化疗后白细胞、网织红细胞及血小板均急剧降低，ANC和RET#会分别降至0.2×109/L和10×109/L以下，HFR加MFR降至最低或是0，对患者进行骨髓细胞学检测结果为：有核细胞发生增生降低或是极度降低现象，LFR对患者造血功能产生抑制影响。结论：对白血病患者的RET#（网织红细胞参数）进行动态监测观察，为判定患者自身的造血功能情况提供更为丰富的临床信息，在临床治疗上具有重要参考价值和意义。