Objective To try to use fetal calf serum (FCS)to prepare hepatitis B virus (HBV)marker external quality assessment material instead of human serum. Methods FCS was used as matrix,and human serum high-level HBV marker external quality assessment material was diluted. The matrix efficiency,interchangeability,homogeneity, stability and clinical application significance were evaluated. Results For the interchangeability of the 2 determination methods,the results were within 95% confidence interval,and the correlation was good. F values were all 展开▼