In order to control the release speed of the drug in the composite fabric and prolong its release process,the Geranium wilfordii Maxim(GWM)extracts were encapsulated into polyvinyl alcohol(PVA) by interfacial polymerization. The GWM microcapsules were coated on cotton knits using water-borne polyurethane(PU)adhesive by direct coating. The morphology,particle size,thermal stabilityand slow-release properties of the microcapsules and the morphology and slow-release properties of the composite fabric were studied using SEM, TG andultraviolet-visible(UV-VIS)spectrophotometer. The results indicate that the surface of GWM/PVA microcapsules is smooth, and the average particle size is 23.9 μm. The GWM/PVA microcapsules with a drug loading ratio of 33.0% show good thermal stability at 325 ℃. The release process following the non-fickian diffusion mechanism can last for more than 24 h in the buffer solution. The release process of the composite fabric follows the similar diffusion mechanism. The release time is prolonged in the buffer solution.%为制备可持续释放,缓释时间较长的载药复合织物,采用界面聚合法,以聚乙烯醇为壁材,中药老鹳草水提取物为芯材制备得到老鹳草微胶囊.以水性聚氨酯为黏合剂,通过干法涂层将老鹳草微胶囊整理到纯棉针织物上制备得到复合织物.采用扫描电子显微镜、热重分析仪、紫外 可见光谱等对老鹳草微胶囊及复合织物的形貌、耐热性、缓释性进行测试与表征.结果表明:老鹳草微胶囊表面光滑,平均粒径为23.9 μm,载药率为33.0%,在325 ℃以下具有较好的热稳定性;制备的老鹳草微胶囊具有缓释性能,其释放遵循非菲克扩散规律,在缓冲溶液中可持续释放24 h以上;复合织物中药物释放遵循同样的规律,在缓冲液中的释放时间有所延长.
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