低体温对严重创伤患者凝血功能及预后的影响研究

摘要

Objective:To investigate the effect on coagulation function and prognosis of patient with severe trauma because of low temperature , and to provide reference for treatment of trauma patients .Methods:Sixty-eight cases of patients with severe trauma were divided into normal temperature group ( 36-38℃) and low temperature group (<36℃) according to the temperature in the first 24 h at being hospitalized .The coagulation indexes and prognosis were compared between two groups .Results: APTT, PT, TT in low temperature group were longer obviously than those in normal temperature group .the Fib, PLT decreased significantly , the D-D increased significantly , the differences were statistically significant (P<0.05).The ISS score, infection rate, DIC incidence and mortality in low temperature group were significantly higher than those in normal group , the differences were statistically significant ( P<0.05).Conclusion:Patients with severe trauma are prone to low temperature ,low temperature may produce adverse effects on coagulation function and prognosis , therefore , positively monitoring the temperature changes , taking effective insulation measures has great significance to reduce patients'mortality and improve their prognosis .%目的：探讨低体温对严重创伤患者凝血功能及预后的影响，为创伤患者的治疗提供参考。方法：选择严重创伤患者68例，根据入院第1个24 h内的体温分为正常体温组（36～38℃）和低体温组（＜36℃），比较两组的凝血功能指标及预后情况。结果：低体温组APTT、PT、TT较正常体温组明显延长，Fib、PLT明显减少，D-D明显增加，差异有统计学意义（ P＜0．05）。低体温组ISS评分、感染率、DIC及死亡率明显高于正常体温组，差异有统计学意义（P＜0．05）。结论：严重创伤患者易发生低体温，低体温对机体凝血功能及预后均可产生不良影响。因此，积极监测体温变化并采取有效保温措施，对降低患者死亡率、改善预后有着重要意义。