Cornell乘积对心电图左室高电压患者的应用价值

摘要

Objective To investigate the influence factors of Cornell product and its clinical value in pa-tients with left ventricular high voltage.Methods 104 patients with left ventricular high voltage were studied and divided into two groups according to Cornell product:Cornell product normal group(n = 78)and Cornell product abnormal group(n=26). Clinical manifestations ,complicaions and ultracardiographic data in these patients were collected and analyzed. Results Chronic kidney disease(CKD)(OR=4.266,95%CI 1.276-14.257,P=0.018) and left ventricular mass index(LVMI)(OR = 1.023,95%CI 1.004-1.043,P = 0.016)were related to Cornell product. Cornell product was positively correlated LVMI appeared(r=0.497,P<0.001). The correlation of Cor-nell product with left ventricularend-diastolic dimension ,interventricular septal thickness and left ventricular poste-rior wall thickness was weak.ROC-AUC of Cornell product for CKD was 0.634,95%CI=0.506-0.780,P=0.039, sensibility 47.8%,and specificity 81.5%. Conclusions LVMI and CKD are independent influence factors of Cor-nell product. Cornell product has a certain diagnositc value for left ventricular hypertrophy ,but it has no associa-tion with the location of ventricular hypertrophy.%目的 探讨心电图Cornell乘积的影响因素及其对左室高电压患者的临床应用价值.方法 入选左室高电压患者104例,根据Cornell乘积分为Cornell乘积正常组(78例)及Cornell乘积异常组(26例).收集两组患者的一般情况(年龄、性别、体质指数),合并疾病及超声心动图资料并进行比较分析.结果 慢性肾脏病(OR=4.266,95%CI 1.276~14.257,P=0.018)及左室质量指数(OR=1.023,95%CI 1.004~1.043,P=0.016)是左室高电压患者中Cornell乘积异常的独立影响因素.Cornell乘积与左室质量指数呈中等程度正相关关系(r=0.497,P<0.001),但与左室舒张末内径、室间隔厚度及左室后壁厚度相关性较弱.Cornell乘积对于慢性肾脏病的ROC-AUC=0.634,95%CI 0.506~0.780,P=0.039,敏感性47.8%,特异性81.5%.结论 左室质量指数及慢性肾脏病是Cornell乘积的独立影响因素.Cornell乘积对于左室肥厚有一定的诊断价值,但与心室肥厚的位置关联不大.