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《中国海洋大学学报(英文版)》
>Influence of Dietary Probiotic Bacillus TC22 and Prebiotic Fructooligosaccharide on Growth, Immune Responses and Disease Resistance against Vibrio splendidus Infection in Sea Cucumber Apostichopus japonicus
Influence of Dietary Probiotic Bacillus TC22 and Prebiotic Fructooligosaccharide on Growth, Immune Responses and Disease Resistance against Vibrio splendidus Infection in Sea Cucumber Apostichopus japonicus
The effects of probiotic Bacillus TC22 (isolated from intestine of infected sea cucumber) and prebiotic fructooligosaccharide (FOS) on growth, immunity and disease resistance in sea cucumber Apostichopus japonicus were studied. Six experimental diets were formulated with combinations of three levels of TC22 (0, 107 and 109 CFU g-1 diet) and two levels of FOS (0 and 0.5%) in a 3 × 2 factorial experiment. At the end of the 8-week feeding trial,animals were challenged by injecting Vibrio splendidus. The results revealed that the specific growth rates (SGR) of sea cucumbers were not affected by TC22 and FOS, or the interaction between TC22 and FOS (P > 0.05). However,there were significant interactions between TC22 and FOS for immune response and disease resistance in sea cucumbers (P 0.05). Therefore, further studies should examine the effects of combinations of other levels of FOS(> 0.5% or < 0.5%) and TC22 on the immunity and disease resistance of sea cucumbers.
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