The foundation has been formed in today’s Nantong upon which an innovative city can be established. In this paper we analyze the major progress, basic features and existing challenges observed through the evolution of Nantong into an innovative city. Based on the analysis, we discuss the strategic positioning, general ideas, target settings and major paths for Nantong’s development. The paper ends up with several proposals for the practitioner’s reference in many as-pects, including organization and leadership optimization, innovation system and mechanism construction, as well as the fo-cus settings for the present situation of Nantong.%南通创新型城市建设取得明显进展：创新型城市建设实现若干具有标志性意义的重大突破、在区域经济发展战略下创新型城市建设获得顶层设计的有力支撑、企业自主创新主体地位稳步提升、知识产权创造与应用在创新型城市建设中的引导作用进一步彰显、孵化园区和载体建设持续扎实推进、高新技术产业和战略性新兴产业快速发展、创新型企业建设取得突破，企业创新平台建设成效显著、进一步建立健全了全市R&D监测和公布体系、科技资源配置社会化机制不断完善；文章从优化组织领导、创新体制机制以及明确当前应着力抓好的重点工作等方面提出了若干意见与建议。
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