Objective To investigate the diagnosis and surgical treatment of azoospermia with ejaculatory duct obstruction (EDO). Methods The clinical data of 16 cases of azoospermia with EDO were retrospectively analyzed. The diagnostic methods included semen analyses, measurement of fructose and neutral a-glucosidase in the seminal plasma, transrectal ultra-sonography (TRUS) , and vasography when necessary. All patients were treated with transurethral resection of ejaculatory duct (TURED) and followed up for 3 - 6 months. Results 14 (87. 5%) showed improved semen parameters and 5 (31. 3%) patients' wives were pregnant. Conclusion Transurethral resection of ejaculatory duct is effective for the treatment of azoospermia with EDO.%目的 探讨经尿道射精管切开治疗射精管梗阻的安全性及临床疗效.方法 分析2008年1月2011年12月收治的16例射精管梗阻性无精子症患者的临床资料,常规精液分析、精浆果糖、中性a葡萄糖苷酶测定及经直肠超声予以诊断,必要时行精道造影检查确诊.16例均采用经尿道射精管切开术治疗,术后随访其疗效.结果 16例均顺利完成手术,术后随访36月,14例(87.5%)精液各项指标均有明显改善,5例(31.3%)配偶妊娠.结论 经尿道射精管切开术是治疗射精管梗阻性无精子症的安全有效的方法,值得临床推广.
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