Botox A早期切口内注射联合减张法对面部小面积瘢痕手术切口恢复效果的影响

摘要

目的 探讨A型肉毒毒素(Botox A)早期切口内注射联合减张法对面部小面积瘢痕手术切口恢复效果的影响.方法 以入院病例号为编号,采用数字表法将300例面部小面积瘢痕手术患者随机分成3组,每组100例.正常组按照常规方法,进行面部局部瘢痕术,术后清洗切口,不做特殊处理,对照组按照常规方法,进行面部局部瘢痕术,术后清洗切口,并从术后至术后3个月行减张治疗,予3M免缝胶布;观察组以同样方法行面部局部瘢痕手术,局部注射Botox A,并从术后即可至术后3个月行减张治疗,予3M免缝胶布.治疗3个月、随访1年时,对患者瘢痕恢复情况进行评估;随访1年,比较治疗有效率.结果 治疗3个月时,观察组VSS(vancouver scar scale)、OSAS(observer scar assessment scale)、PSAS(patient scar assessment scale)分别为5.2±1.4分、14.7 ±2.4分、15.4 ±3.6分,均低于对照组和正常组(P＜0.05);治疗1年后,3组的VSS、OSAS、PSAS均降低,观察组评分低于对照组和正常组(P＜0.05);观察组治愈率82％明显高于对照组63％和正常组52％(P＜0.05);观察组总有效率97％明显高于对照组85％和正常组79％(P＜0.05).结论 Botox A早期切口内注射联合减张法可有效促进面部小面积瘢痕手术切口恢复效果,提高治愈率,满足患者对面部美观的需求.%Objective To investigate the effect of early incision of botulinum toxin type A (A Botox) on the recovery of the incision in the small area of the opposite side of the incision.Methods Totally 300 cases of facial small area scar surgery were randomly divided into three groups according to the random number table,with 100 cases in each group.The pations of normal group according to the conventional method,the facial scar surgery,after the surgery,clean cut,did not do special treatment.The pations of control group were treated according to the conventional method for facial scar surgery,postoperative cleaning of incision,from postoperative to postoperative 3 months reduction treatment,were treated with 3M free seam tape.The pations of observation group in the same way for facial scar surgery,a local injection of Botox and from postoperative to postoperative 3 months reduction treatnent,were treated with 3M free seam tape.After 3 months and 1 years of follow-up,the condition of scar recovery were evaluated.After 1 years of follow-up,the treatment efficiency was compared.Results Treatment for 3 months,the VSS,OSAS,and PSAS of observation group were 5.2 ± 1.4,14.7 ± 2.4,15.4 ±3.6,were lower than those of the control group and those of the normal group (P ＜ 0.05).One year after treatment,the score of VSS,OSAS,and PSAS of three groups were reduced.Those of observation group were lower than those in the control group and those in the normal group (P ＜ 0.05).The cure rate of observation group was 82％,which was significantly higher than that of the control group 63％and that of the normal group 52％ (P ＜ 0.05).The total effective rate of observation group was 97％,was significantly higher than that of the control group 85％ and that of the normal group 79％ (P ＜ 0.05).Conclusion The method of BotoxA early incision injection combined with the reduction method can effectively promote the small area of facial scar surgery incision recovery effect,improve the cure rate,to meet the needs of patients with facial beauty.