肝脏血管周上皮样细胞肿瘤(Pecoma)临床病理分析并文献复习

摘要

目的：：探讨肝脏血管周上皮样细胞肿瘤的临床病理表现及鉴别诊断。方法：回顾其科室诊断的1例肝脏Pecoma的 HE染色表现及免疫组化表达，并复习相关文献。结果：血管周上皮样细胞肿瘤(Pecoma)来源于间叶，组织学表现为肿瘤细胞以上皮样细胞为主，胞浆可透明或嗜酸性，亦可有梭形细胞，间质富于薄壁血管，脂肪细胞少见，免疫组化恒定表达 HMB45。结论：肝脏Pecoma相较发生于肾、肺部位少见，具有特殊的组织学表现及特征的免疫标记表达。生物学行为不确定，手术完整切除为主要治疗手段。%Objective:To investigate clinical pathological manifestations of Perivascular epithelioid cell tumor and diffential diagnosis.Methods:Review the staining manifestation and immunohistochemical expres-sion of Hematoxylin-Eosin of one of the Pecoma in our department and review relevant literature.Results:Pe-coma originated in mesenchyme,histologically ,the tumor cell were mainly found to be epithelioid cell and the cytoplasm can be transparent or eosinophilic and spindle.The stroma were attached to thin-wall vessels.Few adipocyte can be found.The expression of immunohistochemistry was constantly found to be HMB45.Con-clusion:Compared with the pecoma found on kindey and lung,liver pecoma is relatively scarce and it has spe-cial histological expression and immunolabelling expressions for characteristics.The biological behavior is uncertain,and the main therapy is complete surgical resection.