目的：探讨糖尿病性周围神经病（DPN）和酒精中毒性周围神经病（APN）的肌电图特征性表现与差异，为临床肌电图检测的应用提供参考依据。方法：选择58例 DPN患者和30例 APN患者作为研究对象，利用肌电诱发电位仪对患者行神经传导检测（NCS）和交感神经皮肤反应（SSR）检测，并对照分析2组数据的异常率。结果：DPN患者随糖尿病病程延长，NCS及SSR异常率相应升高，且SSR异常率高于NCS（P＜0.05）；APN患者四肢运动、感觉纤维的髓鞘脱失及轴突损伤均非常明显，且各指标异常率明显高于DPN患者（P＜0.05或P＜0.01），但 APN及DPN患者周围神经近端纤维损伤均相对较轻。结论：DPN 和 APN 均有其独特的肌电图表现，早期对这2类疾病进行肌电图检测有利于早期诊断；NCS可辅助鉴别既有糖尿病又有大量饮酒史的患者神经损伤来源。%Objective To study the features and differences of electromyography of diabetic polyneuropathy (DPN) and alcoholic peripheral neuropathy (APN ), and to provide reference basis for the clinical application of electromyography.Methods 58 patients with DPN and 30 patients with APN were used as subjects. Nerve conduction studies (NCS)and sympathetic skin response (SSR)were performed in the patients, all data were analyzed.Results In the patients with DPN, the abnormalities of NCS and SSR were increased with the prolongation of the time diabetes,and the abnormality of SSR was higher than that of NCS(P<0.05).In the patients with APN, both demyelination and axonal loss in motor and sensory nerves were significantly involved, and the abnomalities of NCS and SSR were higher than those of the DPN patients (P<0.05 or P<0.01);but the proximal nerves were just involoved mildly. Conclusion Both DPN and APN have characteristic electrophysiological features.Early electromyography is useful for the early diagnosis of DPN and APN.According to the electrophysiological features of DPN and APN,the reason of peripheral neuropathy in the patients who have diabetes mellitus and alcoholism could be differentiated.
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