慢性疾病的化学预防(Chemoprevention)是降低心脑血管病、癌症、老年脑神经退行性疾病等重大慢性疾病发病率的重要途径.大规模流行病学调查显示足量进食水果蔬菜等食用植物是预防这些重大慢性疾病的有效方法.实验室和临床研究表明,可食用植物中种类繁多的植物化学物质(Phytochemicals)具有抗氧化、抗炎、抑制肿瘤增生、减轻动脉粥样硬化等广泛的生物活性.植物化学物质对人体健康有益的生物活性及植物化学物质之间的协同作用是可食用植物对慢性疾病化学预防作用的基础.可食用植物及中草药含有的植物化学物质由于其有益的生物活性和人体安全性,在重大慢性疾病的化学预防中具有良好的应用前景.%Chemoprevention of chronic diseases is an important strategy to reduce the incidence of major chronic diseases such as cardio-cerebral vascular diseases, cancer, and senile neurodegenerative diseases. A large number of epidemiological studies show that the adequate intake of fruits, vegetables and other edible plants is an effective way to prevent chronic diseases. Laboratory and clinical researches have demonstrated that phytochemicals enriched in edible plants possess a wide spectrum of bioactivities beneficial to human health including anti-oxidation, anti-inflammation, suppression of atherosclerosis and inhibition of tumor growth. These bioactivities of phytochemicals and the synergistic effects among them are considered the basis of observed chemoprevention of chronic diseases by edible plants. Because of their beneficial bioactivities and high safety to human, phytochemicals contained in edible plants, and in part of Chinese herbal medicines as well, present a broad application prospect in the chemoprevention of serious chronic diseases.
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