Application value of four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging in screening fetal congenital heart disease

摘要

Objective:To explore the value of four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging in screening fetal congenital heart disease.Methods: A total of 671 pregnant women at 22-24 gestational weeks from January 2018 to December 2018 were examined by two-dimensional ultrasound and four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging to observe the development of fetal cardiovascular structure and to compare the two methods in terms of diagnostic accuracy, examination time, image quality and new physician training cycle.Results: Cardiac malformations were found in 12 of the 671 fetuses, among which 11 cases were detected by four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging and 1 case was missed. Postnatal echocardiographic reexamination and autopsy confirmed 12 cases of children with cardiac malformation, including 1 case of atrial septal defect (missed diagnosis by four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging), 4 cases of tetralogy of Fallot's disease, 1 case of right ventricular double outlet, 3 cases of left ventricular dysplasia, 2 cases of complete transposition of the great artery and 1 case of tricuspid valve descending malformation. There was no statistically significant difference between four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging and conventional two-dimensional color echocardiography or/and autopsy (P>0.05). In terms of examination time and new physician training, the four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging technique was superior to conventional color ultrasound screening. No statistically significant difference in image quality.Conclusions:The four-dimensional spatiotemporal image correlation and tomographic ultrasound imaging can rapidly and accurately display fetal heart development, and can be used as the main screening method for fetal congenital heart disease in clinical practice.