Effect of immune-enhanced enteral nutrition on inflammatory response and immune function in elderly patients with septic shock

摘要

Objective:To investigate the effect of immune-enhanced enteral nutrition on inflammatory response and immune function in elderly patients with severe septic shock.Methods:From September 2016 to October 2018,58 cases of serious septic shock patients treated in our hospital,were randomly assigned to two groups.A group-enteral nutrition emulsion group(n=29);B group-enteral nutrition mixed suspension group(n=29);The admission day,one week,two week after admission,the index data of patients',inflammation and immune were collected.Results:With the increase of admission time,CD4 and CD4/CD8 levels in the two groups were gradually increased and CD8 levels were gradually decreased.At 1 and 2 weeks after admission,CD4 and CD4/CD8 levels in the observation group were higher than those in the control group(P0.05).C-reactive protein of subjects in the observation group was higher than that in the control group at 2 weeks after admission(P0.05).At 2 weeks after admission,the DAO of subjects in the observation group was higher than that in the control group(P<0.05).Conclusions:Immune-enhancing enteral nutrition is more helpful to control the inflammatory response in patients of serious septic shock,and it's also can modulate the immune function.