Applied research of pediatric pneumonia serum CK, CTnT levels and ECG change characteristics in diagnosis and treatment of disease and prognostic evaluation

摘要

Objective:To study pneumonia infant's serum creatine kinase and troponin T level changes and combined with electrocardiogram analysis to discuss its meaning to pneumonia infant's clinical diagnosis and treatment.Method: 73 cases of pneumonia infants were selected as study group in our hospital from January 2014 to June 2014, meanwhile select 58 cases of healthy infants as control group, to proceed serum CK and CTnT and electrocardiogram examination of both groups.Results: Before treatment, ordinary pneumonia group's CK level rised, CK-MB and CTnT levels significantly rised, 65.71% of children with pneumonia appeared abnormal electrocardiogram, mainly showed atrial premature beats and sinus tachycardia; severe pneumonia group's CK level significantly rised, CK-MB and CTnT levels highly significantly rised, 86.84% of children with pneumonia appeared abnormal electrocardiogram, mainly showed atrial premature beats, sinus tachycardia, bundle-branch block, P-wave high point and so on. After treatment, ordinary pneumonia group's CK, CK-MB and CTnT levels recovered to normal range, ECG returned to normal mostly; severe pneumonia group's CK level obviously returned to normal range, but CK-MB and CTnT levels still exist significant difference. After treatment, severe pneumonia group's CK, CK-MB and CTnT levels were highly significantly lower than before treatment; Compared with ordinary group after treatment, its CK, CK-MB and CTnT levels were higher, but no significant difference, electrocardiogram also returned to normal, only sinus tachycardia and bundle branch block were difficult to return to normal. Conclusion: Serum CK, CK-MB and CTnT levels of pneumonia infants rise along with the aggravation of disease, and ECG level is abnormal, after treatment, most pneumonia infants are cured. This illustrates infant pneumonia could easily cause multiple organ system damage, especially myocardial injury, monitoring CK, CK-MB and CTnT levels, combined with electrocardiogram data has important reference value to the diagnosis of pneumonia.