同轴静电纺再生丝素/丝胶蛋白纤维的制备及其形态结构表征

摘要

模仿蚕丝的组成和结构,利用同轴静电纺丝法制备了以再生丝素蛋白（RSF）为＂芯＂、丝胶蛋白（SS）为＂皮＂的双组分静电纺纤维。通过扫描电镜和透射电镜研究了内层纺丝液流速（Qc）、电压（U）、接收距离（D）以及场强（E）等参数对同轴静电纺RSF/SS纤维形态结构的影响。研究结果表明纤维的平均直径在1400～2100nm左右,皮-芯层结构清晰;Qc对纤维皮-芯层结构的影响较大,过大的内层纺丝液流速会因外层丝胶对内层丝素的包裹不均匀而导致偏芯现象;随E的增加（U增加或D减小）,纤维的直径及其分布显著减小,皮-芯层结构清晰;相同E下,高电压、长距离利于纤维的细化,使直径变细且分布均匀,皮-芯层结构明显。%To biomimic the composition and core-shell structure of natural Bombyx mori silk,regenerated ultra-fine fibers with a core（silk fibroin,SF）-shell（silk sericin,SS） structure were prepared by coaxial electrospinning.The influences of core flow rate（Qc）,applied voltage（U）,distance from capillary to collector（D） and the strength of electric field（E） on the morphology and core-shell structure of RSF/SS fibers were studied using scanning electron microscope（SEM） and transmission electron microscope（TEM）.It was found that the RSF/SS fibers had clear core-shell structure with average diameters from 1400 to 2100nm.The Qc had a great influence on the formation of the core-shell structure.A larger Qc induced an off axis of core fiber or non-coaxiality because of uneven adhesion of SS（shell） on the SF（core） component.Furthermore,with increasing E（increasing U or decreasing D）,both the average diameter and the diameter deviation of the RSF/SS fiber were decreased and the core-shell structure became clearer.While at the same E,the higher U orlonger D facilitated the formation of the uniform RSF/SS fiber and core-shell structure.