Objective To compare safety, short-term and long-term effect of laparoscopic and open radical resection for rectal cancer. Methods Seventy patients with rectal cancer received laparoscopic radical resection were selected as observation group, and other 70 patients with rectal cancer received open radical resection were control group. The safety, oncologic results, part recurrence rate, transfusion rate and survival rate were compared in the twogroups. Results Bleeding quantity, Postoperative intestinal function recovery time, out-of-bed activity time, and length of stay were lower in observation group than those in control group { P <0. 01). There were no significant differences on the number of lymph nodes harvested, length of sample, length of distal margin resected, local recurrence rate, and transfusion rate between two groups ( P >0. 05). The 3-year over-all survival was 83. 7% in observation group, and 84. 4% in control group ( P =0. 73). Conclusion Laparoscopic radical resection for rectal cancer was safe and feasible. The short-term and long-term effect of laparoscopic radical resection can achieve the outcome of open radical resection, or even better than open radical resection.%目的 对比分析腹腔镜与开腹直肠癌根治术的安全性、近期及远期疗效.方法 选择2005年1月至2007年12月本院进行腹腔镜根治术的直肠癌患者共70例作为观察组,选择同期本院进行开腹直肠癌根治术治疗的患者70例进行1∶1配对,通过门诊复查、电话等方式进行随访.对比分析两种治疗方法的安全性、肿瘤学结果、局部复发率及生存率等.结果 观察组术中出血量、术后肠功能恢复时间、进食流质时间、下床活动时间、住院时间均少于对照组(P＜0.01)；两组淋巴结清扫数量、肿瘤标本长度、远切端距离间差异均无统计学意义(P＞0.05);两组局部复发率、转移率间的差异亦无统计学意义(P＞0.05)；观察组和对照组3年累计生存率分别为83.7％和84.4％(P=0.73).结论 腹腔镜根治术安全可行,治疗近期和远期效果能够达到或优于开腹根治术.
展开▼
