乳房脂肪坏死77例临床分析

摘要

Objective To sum up the etiology, pathology, diagnosis and management of patients with fat necrosis of breast ( FNB). Methods The clinical data of 77 cases of FNB confirmed pathologically in our hospital from 1966 to 2010 were analyzed retrospectively. Results All the patients in this series were females with average age of 32. 5 years and 55. 8% of the patients were over 30 years. The main clinical feature was localized breast lump, and' 57 patients (74% ) had a trauma history. Thirty - six cases (46. 8%) of FNB were correctly diagnosed preoperatively;41 cases (53. 2%) were misdiagnosed, in which 32 cases (41.6% ) were misdiagnosed as breast cancer. All 77 patients were treated surgically by the resection of local lump and surrounding fat tissue(0. 5 cm), the breast sector resection, the incision and drainage of fat liquefaction or other methods. All 77 cases were cured and followed up for 1 year to 5 years with no recurrence or cancer. Conclusion FNB is easily misdiagnosed and difficult to be differentiated from breast cancer,thus the surgery or needle biopsy is recommended.%目的 总结乳房脂肪坏死(fat necrosis of beast,FNB)的病因、病理、诊断及治疗经验.方法 回顾性分析1966年至2010年经病理证实的FNB患者77例的临床资料.结果 FNB以乳房局限性肿块为主要表现,有外伤史57例,占74％.FNB术前36例正确诊断(46.8％)；41例(53.2％)误诊,其中32例(41.6％)误诊为乳癌.77例均行手术治疗,分别采用肿块局部及包括周围0.5cm健康脂肪组织切除术、乳房区段切除术、脂肪液化切开引流术等方法.77例均痊愈,随访1～5年,未出现癌变及复发.结论 FNB易误诊,难以与乳癌鉴别,术前应先行肿块切除或穿刺病理检查为上策.