心血管合并症对老年慢阻肺患者死亡风险影响

摘要

Objective To observe the risk of acute exacerbation and death in elderly patients with COPD complicated with cardiovascular disease within 1 years,and to investigate the effect of cardiovascular disease on the prognosis of elderly patients with COPD. Methods The elderly patients with COPD treated in our hospital were divid-ed into four groups. According to whether combined with cardiovascular disease they were divided into the group A and the group B,a total of 100 cases in the group A with cardiovascular disease and 31 without cardiovascular compli-cations in the group B. According to different cardiovascular diseases,the A group was divided into the A1 coronary heart disease group (n=27),the A2 heart failure group (n=24), the A3 arrhythmia group (n=20) and the A4 hypertension group (n=29). All the patients were followed up for 1 years,and the mortality among different groups were compared. Results The number of acute exacerbation and mortality in the group A was significantly higher than that in the group B in 1 year (P<0.05). The number of exacerbations and mortality in 1 year in the group A was the group A2 > the group A1 > the group A3 > the group A4 (P<0.05). Conclusion Cardiovascular dis-ease may increase mortality in elderly patients with COPD within 1 year,especially heart failure.%目的 观察合并心血管疾病的老年慢性阻塞性肺疾病(慢阻肺)患者1年内急性加重及死亡风险,探讨心血管疾病对老年慢阻肺患者预后的影响.方法 选择医院收治的老年慢阻肺患者,依据是否合并心血管疾病分为A、B组,A组合并心血管疾病100例,B组无心血管疾病合并症31例,A组根据不同心血管疾病分为四个亚组A1冠心病组(n=27)、A2心力衰竭组(n=24)、A3心律失常组(n=20)、A4高血压组(n=29),随访1年,比较不同组之间死亡率等.结果 A组1年内急性加重次数、死亡率均明显高于B组(P<0.05);1年内急性加重次数、死亡率在A组四个亚组间比较,A2组>A1组>A3组>A4组(P<0.05).结论合并心血管疾病有可能增加老年慢阻肺患者1年内死亡率,其中心力衰竭的影响最为明显.