重性抑郁障碍或双相障碍患者抑郁发作伴随躁狂症状的临床特征

摘要

目的：：了解重性抑郁障碍( MDD)或双相障碍抑郁发作患者出现躁狂症状的频率和程度。方法：对52例经简明国际神经精神访谈( MINI)、符合《美国精神障碍诊断与统计手册》第4版( DSM-IV)重性抑郁障碍或双相障碍抑郁发作的患者,采用情感障碍评估量表( ADE)评估患者本次抑郁发作中出现的躁狂症状。结果：52例患者中有36例重性抑郁障碍,16例为双相障碍抑郁发作。至少有1条躁狂症状的患者达86.5%(n=45),至少有3条躁狂症状的患者占32.7%(n=17),而没有任何躁狂症状的患者仅占13.5%(n=7)。结论：抑郁发作患者大多存在不同程度的躁狂症状,及时识别这些症状,对诊断与治疗有指导意义。情感障碍评估量表是一个值得应用的评估情感发作的工具。%Objective:To investigate the frequency and intensity of manic symptoms in patients with ma-jor and bipolar depression. Method:We assessed manic symptoms of 52 patients who met diagnostic and sta-tistical manual of mental disorders( DSM-IV) criteria for major depressive disorder or bipolar disorder depres-sive episode with international neuropsychiatric interview( MINI) and the affective disorder evaluation( ADE) . Results:Thirty-six patients met diagnostic criteria for major depressive disorder,and 16 patients for bipolar disorder depressive episode. 86. 5% patients(n=45) had at least one manic symptom,and 32. 7 %(n=17) had three or more manic symptoms. There are 13. 5%patients ( n = 7 ) without any manic symptoms. Conclusion:Most patients in depressive episode had manic symptoms. The affective disorder evaluation is a helpful instrument for assessing affective episode.