Objective To investigate effect of "hospital-Community-family"integration community nursing intervention on prevention and life quality of psychopath .Methods 282 cases of psychopath in our community from January 2011 to De-cember 2012 were selected and randomly divided into two groups ,each 141 cases .The patients in the control group were given routine hospital care intervention ,while given"hospital-Community-Family"integration nursing intervention based on the control group .Compared clinical Global Impression severity score ,prevention and cure efficacy ,and life quality of two groups .Results After intervention ,CGI-S score in two groups were significantly lower ,and CGI-S score in observation group (3 .65 ± 0 .54) was significantly lower than that of control group (4 .46 ± 0 .59) (P<0 .05) .Prevention and cure effi-cacy including guardianship rate ,condition improved rate ,social participation rate and medication compliance of observation group was significantly better than that of the control group (P< 0 .05) .Life quality including physical health ,mental health ,social functioning ,physical life scores in observation group was significantly better than that of the control group (P<0 .05) .Conclusion "Hospital-Community-Family"integration community nursing can effectively improve and control the disease of psychopath ,and effectively enhance the life quality of patients ,worthy promotion .%目的：探讨“医院-社区-家庭”一体化护理干预在社区精神病患者防治中的效果。方法收集我社区2010年1月～2012年12月282例精神病患者，随机分为对照组和观察组，每组141例。对照组给予常规护理干预。观察组在对照组的基础上给予“医院-社区-家庭”一体化护理干预。并对两组干预前后临床总体印象严重程度（CGI-S ）评分、防治效果、生活质量进行比较。结果干预后观察组CGI-S评分为3．65±0．54分，显著低于对照组4．46±0．59分（P＜0．05）；观察组防治效果包括病情好转率、社会参与率和服药依从性均显著优于对照组（P＜0．05）；观察组生活质量包括躯体健康、心理健康、社会功能、物质生活评分显著高于对照组（P＜0．05）。结论“医院-社区-家庭”一体化护理干预能有效的改善和控制精神病患者病情，并能提升患者生活质量。
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