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石南藤化学成分研究

         

摘要

Aim To investigate the chemical constituents of Piper wallichii. Methods Five compounds were isolated by silica gel column chromatography and Sephadex LH-20 gel column chromatography, and the structures of compounds were identified by spectral analysis. Result Five compounds were identified as piperlonguminine (trans, trans) (1), 4-hydroxy-3,5-dimethoxy-benzoic acid (2), galgravin (3), β-sitosterol (4), and daucosterol (5). Conclusion Five compounds were isolated from Piper wallichii for the first time, and compounds 1-3 were isolated from this genus for the first time.%目的对石南藤Piper wallichii化学成分进行研究.方法应用硅胶、葡聚糖凝胶等色谱技术分离纯化,应用波谱技术确定化合物的结构.结果从石南藤中分离得到了5个化合物,分别为piperlonguminine (trans,trans) (1),4-羟基-3,5-二甲氧基-苯甲酸 (2),galgravin (3),β-谷甾醇 (4)以及胡萝卜苷 (5).结论五个化合物均为首次从石南藤中得到,化合物1~3为首次从胡椒属中得到.

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