Objective To investigate the clinical value of Fetal fibronectin Detection in combination with cervical length measurement to predict preterm birth.Methods 120 cases of pregnant women with symptoms of threatened premature labor(Premature birth group 60 cases+ Threatened preterm labor group 60 cases)and 60 cases normal pregnant women with parturient underwent full-term were selected in our hospital from June 2013 to June 2014 admitted. All pregnant women took the fetal fibronectin detection in combination with cervical length measurement, and then compared the diagnosis result with the actual result to judge the clinical value of the indexes to predict preterm birth.Results The positive detection rate of preterm labor group, threatened preterm labor group and control group were respectively 78.3%, 88.3% and 8.3%, and there were significantly differences between two of them(P<0.05).Conclusion Fetal fibronectin and cervical length measurement can effectively improve the positive predictive of threatened premature delivery, premature delivery rate, which do good to pregnancy outcome and be worthy of further promotion in clinical use.%目的：探讨胎儿纤维连接蛋白联合宫颈长度测量预测先兆早产孕妇早产的临床价值。方法选取2013年6月～2014年6月收治的120例先兆早产孕妇（早产组60例＋先兆早产组60例）与同期足月正常妊娠的产妇60例，均行胎儿纤维连接蛋白联合宫颈长度测量，对比各组诊断结果与实际结果的吻合度，判断其临床价值。结果先兆早产组、早产组及对照组的阳性检测率分别为78.3%、88.3%和8.3%，先兆早产组和早产组的阳性率均显著高于对照组，差异均具统计学意义（P＜0.05）。结论胎儿纤维连接蛋白联合宫颈长度测量能够有效提高对先兆早产孕妇早产的阳性预测率，有利于改善产妇的妊娠结局。
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