Objective To determine the incidence of patients with chronic lymphocytic thyroiditis (CLT) coexisting with thyroid cancer in our institution, and surgical indication of CLT with nodules. Methods Clinical data were collected and analyzed from patients undergoing thyroidectomy and pathologically proved CLT coexisting with thyroid cancer at China Medical University from Oct. 2004 to Sep. 2010. Results The incidence of CLT coexisting with thyroid cancer in this study is 35.99%( 104/289). 27.88% cases were correctly diagnosed before operation. 96.15% of patients were found thyroid nodules and 80.77% of them were calcification. All the patients underwent surgical procedure, only 5 (4.8%) of whom relapsed in 2 years. Conclusion CLT may be a precursor of thyroid cancer. Surgical treatment should be considered for CLT coexisting with nodules, especially those with calcification and/or ECT proving "cold nodule". The surgical procedure of CLT coexisting with thyroid cancer should follow the principle of radical surgery of thyroid cancer.%目的 探讨我院慢性淋巴细胞性甲状腺炎(CLT)合并甲状腺癌的发病率及CLT合并结节的手术指征.方法 回顾分析我院2004年10月至2010年9月期间104例CLT合并甲状腺癌的临床资料.结果 本组CLT合并甲状腺癌的发生率为35.99％( 104/289).术前正确诊断率为27.88％.超声提示96.15％患者伴有甲状腺结节,80.77％伴有钙化.本组患者均行手术治疗,效果良好,5例(4.8％)于术后2年内复发.结论 CLT可能是甲状腺癌的前期病变.对CLT合并甲状腺结节者应考虑手术治疗,尤其术前超声提示钙化和/或ECT提示为“冷结节”者.对于CLT合并甲状腺癌的手术应采取甲状腺癌根治性手术的原则进行手术.
展开▼
