心脏术后心房颤动研究进展

摘要

术后心房颤动(postoperative atrial ifbrillation，POAF)是心脏手术后最常见的并发症，可以引起血流动力学紊乱，增加住院时间和死亡率。目前认为POAF的发生与心肌传导细胞损伤、交感神经系统过度紧张和炎性反应有关。临床上可以通过术前、术中及术后相关指标预测POAF的发生。对于POAF，特别是高风险病人，应该以预防为主，治疗原则是控制心室率、抗凝和转复心律。%Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, which leads to hemodynamics disorder, prolongs hospitalization and increases mortality. The underlying mechanisms behind POAF are associated with cardiomyocyte injury, sympathetic activation and inflammation. The prediction of POAF is based on correlated index from pre-, intra-and post-surgery. POAF can be treated by rhythm and heart rate control as well as and antithrombotic therapy.