偏头痛脑白质异常的 MRI 表现

摘要

Objective To study the MRI findings of cerebral white matter abnormalities inpatients with migraine.Methods We selected seventy patients ( 51 women, 15 men) with migraine whose age ranged between 18-50(mean 36.21±8.9) and 70 healthy controls (53 women, 17 men) whose age ranged between18-50(mean35.32 ±8.6) .All subjects were performed by MRI.Data were analyzed by the SPSS13.0.Results MRI showed 23 cases of cerebral white matter abnormalities in migraine group, which performed as equal signals on T1 , high signals on T2 and FLAIR in subcortical cerebral white matter; while only 6 cases in control group.The rate of cerebral white matter abnormalities in migraine group( 32.86%, 23/70) was obviously higher than that in control group( 8.57%, 6/70) (χ2=12.57, P<0.01).In migraine group, the rate of cerebral white matter abnormalities in patients with aura (48.39%,15/31) was obviously higher than that in patients without aura (20.51%, 8/39) (χ2=6.08, P<0.05). Conclusion The incidence of cerebral white matter abnormalities in patients with migraine is higher, and which with aura is much higher than without.%目的：探讨偏头痛脑白质异常（ WMAs）的MRI表现。方法选取70例偏头痛患者并行MRI检查，女性51例，男性19例，年龄为18～50岁，平均年龄36．21±8．9岁。选取同期健康体检者并行MRI检查70例对照组，女性53例和男性17例，年龄为18～50岁，平均年龄35．32±8．6岁。运用SPSS13．0软件对数据进行分析。结果显示偏头痛组中有23例WMAs，表现为皮质下脑白质内等T1长T2信号影，Flair高信号；对照组中有6例WMAs。偏头痛组WMAs的比例（32．86％，23／70）明显高于对照组（8．57％，6／70）（χ2＝12．57，P＜0．01） 。偏头痛组中有先兆偏头痛患者WMAs的比例（48．39％，15／31）明显高于无先兆偏头痛患者（20．51％，8／39）（χ2＝6．08，P＜0．05）。结论偏头痛患者WMAs的发生率较高，且有先兆偏头痛患者较无先兆偏头痛患者更高。