养血饮口服液对免疫系统的影响

摘要

Objective To observe the effect of Yangxueyin oral liquid on immune system.Methods Kunming mice of SPF grade, half male and half female.Yangxueyin was administered at a dose of 10.4 mL/kg, 5.2 mL/ kg or 2.6 mL/kg for 10 days. Cyclophosphoryl was injected intraperitoneally from the 6th day, and the model was made for 5 days. The positive control group was compound E'jiao oral liquid, weighing it for 0, 5 and 10 days, weighing it for the last time, calculating spleen, thymus organ index and white blood cell count, and measuring lymphocyte transformation rate.Results In the model group, the body weight, spleen and thymus index, and the number of white blood cells were significantly decreased. Splenic lymphocyte transformation rate decreased significantly.Yangxueyin significantly increased the weight, thymus and spleen fingers, and white blood cells in mice. Splenic lymphocyte transformation rate increased significantly.Conclusion Yangxueyin oral liquid can enhance immune function.%目的 观察养血饮口服液对免疫系统的影响.方法 SPF级昆明种小鼠,雌雄各半,养血饮按剂量10.4、5.2、2.6 mL/kg给药10 d;从第6天开始腹腔注射环磷酰胺,共造模5 d;阳性对照为复方阿胶口服液,于0、5、11 d称重,末次给药称重并计算脾脏、胸腺脏器指数和白细胞数目,测定淋巴细胞转化率.结果 模型组小鼠体质量、脾脏和胸腺指数、白细胞数目明显地减少;脾淋巴细胞转化率明显降低;养血饮可使小鼠体质量、胸腺和脾脏指、白细胞数目显著增加;显著升高脾淋巴细胞转化率.结论 养血饮口服液具有增强免疫功能作用.