经鼻持续气道气道正压通气(N-CPAP)治疗新生儿呼吸衰竭的临床研究

摘要

目的 探讨经鼻持续气道正压通气( N-CPAP)治疗新生儿呼吸衰竭的疗效。方法 在综合治疗同时应用NCPAP治疗新生儿呼吸衰竭60例，动态观察分析患儿在NCPAP前后的临床表现、动脉血气、经皮氧饱和度( Sa02)的变化。结果 60例呼吸衰竭患儿应用NCPAP后有49例临床表现明显好转，SaO2＞ 0.9，血气Pa02明显提高（P＜0.01）。PaCO2显著下降(P＜0.05)。结论 NCPAP可以改善氧合和通气，对新生儿呼吸衰竭有较好疗效。%Objective To clinical study the curative effect of nasal continuous positive airway pressure(NCPAP) in treatment of neonatal respiratory failure. Methods 60 neonates who suffered from respiratory failure were cured by NCPAP treatment on the basis of comprehensive treatment, the dynamic changes of clinical manifestation, PaO2 and SaO2 were observed before and after the treatment. Results After the treatment, clinical manifestation were markedly improved, SaO2 increased (P＜ 0.01) and PaO2 decreased (P ＜ 0.05) obviously in 49 cases. Conclusions NCPAP treatment can improve the oxygenation with significant effect, has a good effect on neonatal respiratory failure.