低分子肝素钙治疗肺心病合并呼吸衰竭患者的临床效果

摘要

Objective To investigate the clinical effect of low molecular heparin calcium in the treatment of cor pulmonale complicated with respiratory failure.Methods 68 patients with cor pulmonale complicated with respiratory failure were selected from our hospital.The patients were numbered;in accordance with the even number,the patients were divided a control group and an observation group,34 cases for each group.The control group were conventionally treated;in addition,the observation group were treated with low molecular heparin calcium.The clinical curative effect and arterial blood gas changes were compared between these two groups before and after the treatment.Results The total effective rate was 97.1％ in the observation group and 76.5％ in the control group,with a statistical difference (P＜0.05).There were no statistical differences in arterial blood gas and pH between these two groups before the treatment (P＞0.05).There were great changes in PaCO2 and PaO2 in both groups and greater in the observation group than in the control group.After the treatment,there were statistical differences in PaCO2 and PaO2 between these two groups (P＜0.01).Conclusions Low molecular heparin calcium for patients with cor pulmonale complicated with respiratory failure is significantly effective and can significantly improve the patients' cardiopulmonary function,correct hypoxia,and enhance myocardial contraction force.It is worth being clinically generalized.%目的 探讨低分子肝素钙治疗肺心病并呼吸衰竭的临床效果.方法 选取本院收治的肺心病并呼吸衰竭患者68例,对患者进行编号,按照奇偶数分为对照组和观察组,各34例.对照组常规治疗,观察组在对照组基础上加用低分子肝素钙治疗.比较两组临床疗效及治疗前后动脉血气变化情况.结果 观察组治疗总有效率为97.1％,对照组为76.5％,差异有统计学意义(P＜0.05).治疗前,两组动脉血气、pH值比较,差异无统计学意义(P＞0.05);两组治疗后动脉血气PaCO2、PaO2值较治疗前有显著变化,但观察组变化较对照组更明显,两组治疗后动脉血气PaC02、Pa02值比较差异具有统计学意义(P＜0.01).结论 低分子肝素钙治疗肺心病合并呼吸衰竭效果明显,能明显改善患者心肺功能,纠正缺氧,增强心肌收缩力,值得临床进一步推广.