自拟汤剂脑得康2号对基底节高血压脑出血术后昏迷患者的临床疗效观察

摘要

Objective To observe the clinical curative effect of No.2 brain rehabilitation decoction for patients with coma after the operation of hypertensive cerebral hemorrhage in basal ganglia.Methods 72 patients with coma the operation of hypertensive cerebral hemorrhage in basal ganglia were selected and randomly divided into a control group and an observation group,36 for each group.The control group were intravenously dripped naloxone,once a day;in addition,the observation group orally took No.2 brain rehabilitation decoction,3 times a day.Before the treatment and after 15 days' treatment,basilar artery (BA) indexes,systolic peak velocity (VS) and mean velocity (VM) were detected and recorded in both groups.The consciousness recovery time,Glasgow Pittsburgh scores,and Glasgow Coma Scale (GCS) score of both groups were recorded.The indicators above were statistically compared.Results After the treatment,the consciousness recovery time was significantly shorter in the observation group than in the control group (P ＜ 0.05).The Glasgow Pittsburgh score,GCS score,VS,and VM were significantly higher after than before the treatment in both groups(P ＜ 0.05) and were(28.89 ± 2.59),(15.87 ± 2.01),(60.65 ± 7.32)cm/s,and (48.09 ± 5.40)cm/s in the observation group and better than in the control group (P ＜ 0.05).Conclusions No.2 brain rehabilitation decoction for patients with coma after the operation of hypertensive cerebral hemorrhage in basal ganglia can shorten the course of disease.Its cured rate is high.Tt is worth being clinically generalized and studied.%目的 观察脑得康2号治疗基底节高血压脑出血术后昏迷患者的临床疗效.方法 选取72例基底节高血压脑出血术后昏迷患者随机分为对照组和观察组,各36例.对照组患者术后24 h内静脉点滴纳洛酮,每日1次;观察组患者采用两种药物联合治疗方法,给予患者口服自拟汤剂脑得康2号,每天3次.连续治疗半个月后,检测并记录治疗前后检测两组患者基底动脉(BA)、收缩峰值流速(Vs)及平均流速(Vm);记录两组患者意识恢复的时间、Glasgow-Pinsburgh评分及GCS评分,并将以上指标进行统计比较.结果 治疗后治疗组的意识恢复时间与对照组比较明显缩短(P＜0.05);两组患者Glasgow-Pittsburgh评分、GCS评分、Vs及Vm均较治疗前显著增高(P＜0.05),并且治疗组的Glasgow-Pittsburgh评分为(28.89±2.59)分,GCS评分为(15.87±2.01)分,Vs及Vm分别为(60.65±7.32) cm/s、(48.09±5.40)cm/s,以上指标均显著高于对照组(P＜0.05).结论 脑得康2号可以促进基底节高血压脑出血术后昏迷患者的清醒,缩短病程,治愈率高,值得临床进一步推广研究.