阴道B超下子宫内膜形态与试管婴儿临床妊娠的相关性研究

摘要

Objective To analyze the correlation between endometrial morphology and the clinical pregnancy rate of test-tube baby under the transvaginal ultrasonography. Methods The clinical data about 84 puerperae receiving the test-tube baby from January 2014 to June 2016 in reproductive medicine department of our hospital was reviewed. The correlation between endometrial type and thickness on the day of HCG administration and the retrieval and the clinical pregnancy rate were analyzed. Results The age, infertility type, infertility reasons, FSH counts during the treatment, the number of oocyte, the number of embryo transplantation, and the endometrial thickness [(11.89±4.06)mm vs.(10.81±4.59)mm] of pregnancy group and non-pregnancy group were not significantly different (P>0.05). On the day of the retrieval, the endometrial thickness of pregnancy group and non-pregnancy group were (11.44±3.91)mm and (12.98±5.25)mm (P>0.05); on the day of HCG administration, the rate of endometrial thickness ≥12mm of pregnancy group [73.8％ (31 cases)] was significantly higher than that of non-pregnancy group [52.4％ (22 cases)], the rate of endometrial thickness <7 mm of pregnancy group [2.4％(1 case)] was significantly lower than that of non-pregnancy group [19.0％ (8 cases)]. On the day of the retrieval, the rate of type B endometrium of pregnancy group [69.0％ (29 cases)] was significantly higher than that of non-pregnancy group [42.9％ (18 cases)], with statistically significant difference (P<0.05). Conclusion The pregnancy rate is increased for patients with endometrial thickness ≥12mm on the day of HCG administration and patients with type B endometrium on the day of the retrieval; based on the transvaginal ultrasonography, the detection of the endometrial morphology is good to predict the clinical pregnancy rate of test-tube baby.%目的 探讨分析经阴道超声测量子宫内膜形态与试管婴儿临床妊娠成功率的关系.方法 本研究回顾性分析2014年1月至2016年6月于本院生殖医学科接受试管婴儿的84例产妇临床资料,比较分析HCG注射日和取卵日经阴道超声子宫内膜类型及厚度与临床妊娠结果的相关性.结果 妊娠组患者与非妊娠组患者在年龄、不孕类型、不孕原因、治疗过程中使用的FSH支数、取卵数及胚胎移植数量等方面比较差异无统计学意义(P>0.05),而子宫内膜厚度分别为(11.89±4.06)mm和(10.81±4.59)mm,组间比较差异无统计学意义(P>0.05);取卵日,妊娠组患者与非妊娠组患者子宫内膜厚度分别为(11.44±3.91)mm和(12.98±5.25)mm,组间比较差异无统计学意义(P>0.05).后续研究具有可比性.妊娠组HCG注射日内膜厚度≥12 mm患者31例(73.8％),显著高于非妊娠组的22例(52.4％);内膜厚度<7 mm患者1例(2.4％),显著低于非妊娠组的8例(19.0％).取卵日子宫内膜B型数量29例(69.0％),显著高于非妊娠组的18例(42.9％),差异有统计学意义(P<0.05).结论 HCG注射日子宫内膜≥12 mm及取卵日B型子宫内膜患者妊娠成功率较高,阴道B超监测子宫内膜形态有助于预测试管婴儿妊娠成功.