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首页> 外文期刊>国际眼科杂志：英文版 >Clinicopathologic features and prognostic factors of malignant eyelid tumors
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Clinicopathologic features and prognostic factors of malignant eyelid tumors

机译：恶性眼睑肿瘤的临床病理特征和预后因素

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机译：·AIM: To investigate the clinical characteristics and prognosis of patients with malignant eyelid tumors. ·METHODS: This was a retrospective, non-randomized, clinical reviews. Between January, 2002 and December, 2011, 75 cases with histologically confirmed malignant eyelid tumors were evaluated. Patients’ charts were reviewed for clinical information, treatment procedure, and disease course. Survival analysis in terms of recurrence -free survival was performed using age, sex, location of tumor and histopathological type. The followup ranged from 1 to 78 months (mean=21 months). ·RESULTS: The 75 eyelid tumors included 35 basal cell carcinoma (BCC, 46.7%), 22 sebaceous gland carcinoma (SGC, 29.3% ), 7 squamous cell carcinoma (SCC, 9.3% ), 10 malignant melanoma (MM, 13.3% ), and 1 Merkel cell carcinoma (MCC, 1.3% ). Recurrence developed in 17 cases (22.7% ). The recurrence rate of BCC (4/35, 11.4% ) was significant lower than MM (6/10, 60.0% , <0.001).The mean interval of recurrence was 21 months (range 362) for all eyelid tumors. Tumor located at canthus had higher recurrence rate (50% ) compared with those located at eyelid (19% , <0.05). Histological type was independent variable for recurrence by Cox regression analysis. ·CONCLUSION: It is important to achieve a negative tumor margin in canthus located malignant eyelid tumor. Clinicians should have a high level of suspicion for recurrence according to histological type when treating patients with eyelid tumor.

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