多模态MRI在定量评价脂肪组织和脂肪肝中的研究进展

摘要

脂肪代谢异常与机体代谢性疾病和炎症反应的发生和发展密切相关,可引起全身多脏器功能障碍.传统的脂肪组织检查方法多为有创性检查,多模态MRI技术能够对脂肪组织的功能以及异位脂质沉积进行全面的评估,可为脂肪相关代谢性疾病的诊断、疾病进展监测和治疗效果的评价提供大量信息.就多模态MRI技术在定量评价脂肪组织和脂肪肝中的技术进展与研究现状进行综述.%Abnormal fat metabolism plays an important role in the initiation and development of systemic metabolic diseases and inflammation response, which can lead to multiple organ dysfunction. Traditional methods for analyzing adi-pose tissue (AT) are all invasive approaches. Multimodal magnetic resonance imaging (MRI) can provide a comprehensive assessment of the function of AT, ectopic fat deposition, and can provide abundant information for diagnosis, monitoring disease progression, and evaluation of therapeutic efficacy of metabolic diseases. This article aimed to review technological advances and research application of multimodal MRI in quantitative evaluation of fat tissue and fatty liver.