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纳米佐剂疫苗的特点与应用

         

摘要

纳米材料具有特殊的物理和化学性质,在各个领域的应用日益广泛.因其具有良好的生物相容性、生物靶向作用和较高的生物利用度,可将其作为疫苗佐剂的载体.纳米材料能快速有效地靶向于特定部位,提高新型疫苗的免疫原性,避免在肝脏内的首关消除作用,降低其毒副作用.纳米疫苗在预防和治疗疾病方面有广阔的发展前景.%Nanometer material have been widely used in a number of fields because of their diversified physical and chemical effects.Owing to their good biocompatibility,well targeting property and high bioavailability,they are considered as a good support for vaccine adjuvant.In short,it has a targeting function to specific parts,can improve the immunogenicity of new vaccine,avoid first-pass metabolism in the liver and then has less side effect.With these advantages,it has shown a proved potential application for disease control and treatment.So some unique properties of nano-materials are reviewed,with a look forward to the future of their application technology in the areas of and medicine.

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