Objective: To investigate the vetrebrai artery's blood flow change in patients with Takayasu arteritis. Method: GE Vivid7 computed sonography,2.0-7.0MHz transducer frequency were used for routine examination in 30 patients with Takayasu arteritis ( the study group ) and in 30 cases who age-matched healthy persons. Measured 2-dimensional and doppler flow indexes by CDFI in the two groups. Result: The morphologic constructions of the vessels and indexes of color doppler flow in study group were more different from those in control group. All of walls of carotid arteritis in study group have thickness and CDFI of these patients had vascular stenosis. Among them, there were 11 common carotid , 6 subclavian and 13 cases with both of the above two types. The thickness of the involved artery wall was stenosed or occluded. The affected vertebral arterial systolic velocity decreased in patients with subclavian arterial severe stenosis and occlusion when compared with patients with mild-to-moderate stenosis, and further decreased in patients with subclavian arterial occlusion. There was significant difference between two groups （ P＜0.05 ). Conclusion: The involvement extent of subclavian artery stenosis can be reflected by the features of doppler spectrum and systolic velocity of affected vertebral artery in paients with Takayasu arteritis.%目的:应用彩色多普勒超声检查头臂型大动脉炎不同病变类型的椎动脉血流变化.方法:选择2003年至2010年门诊及住院患者30例,均经DSA检查及临床检查证实,常规进行颈动脉、锁骨下动脉及椎动脉的检查.测量病变血管内中膜厚度及残余内径,彩色多普勒观察血流状态,方向及狭窄部位的血流参数.结果:所有病例均有不同程度的血管狭窄,其中单纯颈动脉狭窄11例,轻度狭窄椎动脉内径及血流无明显改变,中度以上至闭塞,椎动脉均出现不同程度的扩张,血流增快,差异有统计学意义( P＜0.05);单纯锁骨下动脉狭窄6例,二者均不同程度的存在13例;轻度狭窄的流速峰值无显著改变,狭窄中度至闭塞的流速峰值表现为峰值降低,(P＜0.05),呈不同程度的椎动脉窃血现象.结论:供应脑部的血管有高度的自主调节能力,椎动脉多普勒血流频谱特征及收缩期峰值流速降低可以间接反映同侧锁骨下动脉狭窄的程度.
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